Pharmacology API

Pharmacology API for fetching pharmacology information related to drugs by Drugbank
The pharmacology API by Drugbank holds data with the goal of fetching pharmacology information related to drugs. It is exciting to read about new projects that use this pharmacology API, you can realise a few business cases with this data but several examples are; healthcare marketing, pharmaceutical comparison and analysis, providing information about drugs on healthcare platforms, healthcare research and more. Developers often think of new ways to take advantage of the data from the API system and design new projects with it. Certain examples of the potential filters are indication, pharmacodynamics, mechanism_of_action, absorption, toxicity, protein_binding and more, use these to decide the API response. The database has coverage in Austria, Canada, Colombia, European Union, Indonesia, Italy, Malaysia, Singapore, Thailand, Turkey and United States. The API is used by small business, medium business and enterprises, some ideas of the type of company that uses the API are healthcare marketing platforms, pharmaceutical companies, drug directory services and more. The customers use it within the healthcare, marketing and pharmaceutical industry.

Pharmacology API endpoints


Endpoint Unknown

To receive a data output like in the example output, clients need to communicate to the pharmacology API endpoint by sending a request to the endpoint; with the required parameters. Input the API endpoint in the URL to apply for the data request. The API documentation works with all main coding languages, simply add the API key parameter to the data endpoint URL and set it to your private API key to start receiving the required data. To receive the output required, make use of the parameters and objects as described by the table.

Pharmacology API filter parameters

The pharmacology API has the below mentioned filters applicable that can be filtered with.
indication protein_binding clearance
pharmacodynamics metabolism structured_indications
mechanism_of_action half_life
absorption route_of_elimination
toxicity volume_of_distribution

Data attributes for pharmacology API

Generate a data request with the possible parameters and use the table to clarify the objects with their description.
Objects Description
indication The approved conditions, diseases, or states for which a drug can safely and effectively be used. An indication is considered to be FDA-approved when it has any of the following designations: NDA, ANDA, BLA, or OTC. May also include indications in other countries, such as Canada (through Health Canada) or in Europe (through the European Medicines Agency).
pharmacodynamics A description of how the drug modifies or affects the organism it is being used in. May include effects in the body that are desired (enzyme or protein targets for example) and undesired (also known as “side effects”). This is in contrast to pharmacokinetics, which describes how the body modifies the drug being used.
mechanism_of_action A component of pharmacodynamics that describes the biochemical interaction through which a drug produces its intended effect. May include the exact molecular protein or enzyme targets and/or a description of the physiological effects produced.
absorption A description of the movement of the drug from the site of administration into the bloodstream or target tissue. Common pharmacokinetic metrics used to evaluate absorption include Area Under the Curve (AUC), bioavailability (F), maximum concentration (Cmax), and time to maximum concentration (Tmax).
toxicity Any adverse reaction, or side effect, that may or may not occur with use of the drug. May be attributed to a number of effects including: an enhanced therapeutic effect, rare anaphylactic reactions, interactions with other medications, or unanticipated binding of the molecule at different sites within the body.
protein_binding A description of the drug’s affinity for plama proteins and the proportion of the drug that is bound to them when in circulation within the body.
metabolism A description of the chemical degradation of the drug molecule within the body; most commonly by enzymes from the Cytochrome P450 (CYP) system in the liver.
half_life The period of time it takes for the amount of drug in the body to be reduced by one half. Provides a description of how quickly the drug is being eliminated and how much is available in the bloodstream.
route_of_elimination A description of the pathway that is used to excrete the drug from the body. Common pharmacokinetic parameters used to evaluate excretion include elemination half life, renal clearance, and tracking of radiolabelled compounds through the renal and GI system.
volume_of_distribution The Vd of a drug represents the degree to which it is distributed into body tissue compared to the plasma.
clearance A pharmacokinetic measurement of the rate of removal of the drug from plasma, expressed as mL/min; reflects the rate of elimination of the drug.

Pharmacology API output response

Here is an example data response of the endpoint request. More data is available, this example is limited to make it more readable. Opt-in to the API system to gain access to the complete data response.
  "pharmacology": {
    "indication": "Gadobenate Dimeglumine is an MRI contrast agent used primarily for MR imaging of the liver. It can also be used for MRI of the heart, as well as and central nervous system in adults to visualize lesions with abnormal brain vascularity or abnormalities in the blood brain barrier, the brain, spine, or other associated tissues.",
    "pharmacodynamics": "Gadobenate dimeglumine shares the pharmacokinetic properties of the ECF contrast agent gadopentetate dimeglumine; however, gadobenate differs in that is also selectively taken-up by hepatocytes and excreted via the bile (up to 5% of dose). The elimination half-life of gadobenate dimeglumine is approximately 1 hour. It is not metabolized.",
    "mechanism_of_action": "Based on the behavior of protons when placed in a strong magnetic field, which is interpreted and transformed into images by magnetic resonance (MR) instruments. Paramagnetic agents have unpaired electrons that generate a magnetic field about 700 times larger than the proton's field, thus disturbing the proton's local magnetic field. When the local magnetic field around a proton is disturbed, its relaxation process is altered. MR images are based on proton density and proton relaxation dynamics. MR instruments can record 2 different relaxation processes, the T1 (spin-lattice or longitudinal relaxation time) and the T2 (spin-spin or transverse relaxation time). In magnetic resonance imaging (MRI), visualization of normal and pathological brain tissue depends in part on variations in the radiofrequency signal intensity that occur with changes in proton density, alteration of the T1, and variation in the T2. When placed in a magnetic field, Gadobenate Dimeglumine shortens both the T1 and the T2 relaxation times in tissues where it accumulates. At clinical doses, Gadobenate Dimeglumine primarily affects the T1 relaxation time, thus producing an increase in signal intensity. Gadobenate Dimeglumine does not cross the intact blood-brain barrier; therefore, it does not accumulate in normal brain tissue or in central nervous system (CNS) lesions that have not caused an abnormal blood-brain barrier (e.g., cysts, mature post-operative scars).",
    "absorption": "",
    "toxicity": "Gadolinium-based radiocontrast agents like gadobenate dimeglumine are cytotoxic to renal cells. The toxic effects include apoptosis, cellular energy failure, disruption of calcium homeostasis, and disturbance of tubular cell polarity, and are thought to be linked to oxidative stress.",
    "protein_binding": "Plasma protein binding is low, weak, and transient.",
    "metabolism": "Not metabolized.",
    "half_life": "1 hour",
    "route_of_elimination": "Gadobenate ion is eliminated predominately via the kidneys, with 78% to 96% of an administered dose recovered in the urine.",
    "volume_of_distribution": "",
    "clearance": "* 0.093 +/- 0.010 L/hr/kg [healthy male subjects receiving 3 single-dose IV administration with doses from 0.005-0.4 mmol/kg]",
    "structured_indications": [ ]


There are SDKs accessible to help the designing of your system, just request them and they should be emailed. After this use the filter parameters to choose the required output for you and with the pharmacology API output in JSON your project is easy to develop.

Pharmacology API pricing

Make contact with the data provider to inquire into access to samples and trials of the data so that you are able to try the data ahead of deciding to purchase the full package access. The test access is limited but will be able to provide you with a decent insight into the complete system.

API pricing

The API by Drugbank is accessible with 3D secure payment option and instant access to get data.
Price upon request

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