Pharmacology API

Pharmacology API for fetching pharmacology information related to drugs by Drugbank
The pharmacology API of Drugbank delivers data with the purpose of fetching pharmacology information related to drugs. The API is available for Austria, Canada, Colombia, European Union, Indonesia, Italy, Malaysia, Singapore, Thailand, Turkey and United States. Some projects for the drug effects data are for example; healthcare marketing, pharmaceutical comparison and analysis, providing information about drugs on healthcare platforms, healthcare research and more. It is ofcourse a possibility that people have unique use cases which weren’t thought of previously. It is interesting to hear about them. A few examples of the type of company who uses it are healthcare marketing platforms, pharmaceutical companies, drug directory services and more, usually the clients are small business, medium business and enterprises within the healthcare, marketing and pharmaceutical industry. A few examples of the possible filters are indication, pharmacodynamics, mechanism_of_action, absorption, toxicity, protein_binding and more, use these to decide the data response.

Pharmacology API endpoints


Connect with the drug effects API endpoint; by sending a GET request for data to the endpoint using the the available parameters and obtain an response like in the example output as a response. The endpoint is used for fetching pharmacology information related to drugs. Put the data endpoint into the URL to execute the data request. In order to obtain the response desired, make use of the objects and parameters as described by the parameter table. Working with your API key parameter and connecting to it with your personal key, you can start receiving data by using any of the major programming languages.

Data filters for pharmacology API

Find here the filters available for the pharmacology API.
indication protein_binding clearance
pharmacodynamics metabolism structured_indications
mechanism_of_action half_life
absorption route_of_elimination
toxicity volume_of_distribution

Data object attributes

Clarify the objects and the associated description by using the table to use the API also make use of the available parameters to be able to obtain the desired response output.
Objects Description
indication The approved conditions, diseases, or states for which a drug can safely and effectively be used. An indication is considered to be FDA-approved when it has any of the following designations: NDA, ANDA, BLA, or OTC. May also include indications in other countries, such as Canada (through Health Canada) or in Europe (through the European Medicines Agency).
pharmacodynamics A description of how the drug modifies or affects the organism it is being used in. May include effects in the body that are desired (enzyme or protein targets for example) and undesired (also known as “side effects”). This is in contrast to pharmacokinetics, which describes how the body modifies the drug being used.
mechanism_of_action A component of pharmacodynamics that describes the biochemical interaction through which a drug produces its intended effect. May include the exact molecular protein or enzyme targets and/or a description of the physiological effects produced.
absorption A description of the movement of the drug from the site of administration into the bloodstream or target tissue. Common pharmacokinetic metrics used to evaluate absorption include Area Under the Curve (AUC), bioavailability (F), maximum concentration (Cmax), and time to maximum concentration (Tmax).
toxicity Any adverse reaction, or side effect, that may or may not occur with use of the drug. May be attributed to a number of effects including: an enhanced therapeutic effect, rare anaphylactic reactions, interactions with other medications, or unanticipated binding of the molecule at different sites within the body.
protein_binding A description of the drug’s affinity for plama proteins and the proportion of the drug that is bound to them when in circulation within the body.
metabolism A description of the chemical degradation of the drug molecule within the body; most commonly by enzymes from the Cytochrome P450 (CYP) system in the liver.
half_life The period of time it takes for the amount of drug in the body to be reduced by one half. Provides a description of how quickly the drug is being eliminated and how much is available in the bloodstream.
route_of_elimination A description of the pathway that is used to excrete the drug from the body. Common pharmacokinetic parameters used to evaluate excretion include elemination half life, renal clearance, and tracking of radiolabelled compounds through the renal and GI system.
volume_of_distribution The Vd of a drug represents the degree to which it is distributed into body tissue compared to the plasma.
clearance A pharmacokinetic measurement of the rate of removal of the drug from plasma, expressed as mL/min; reflects the rate of elimination of the drug.

Output response of the pharmacology API

Sign-up to the system to request the complete data responsebut you can already find part of the output on this page.
  "pharmacology": {
    "indication": "Gadobenate Dimeglumine is an MRI contrast agent used primarily for MR imaging of the liver. It can also be used for MRI of the heart, as well as and central nervous system in adults to visualize lesions with abnormal brain vascularity or abnormalities in the blood brain barrier, the brain, spine, or other associated tissues.",
    "pharmacodynamics": "Gadobenate dimeglumine shares the pharmacokinetic properties of the ECF contrast agent gadopentetate dimeglumine; however, gadobenate differs in that is also selectively taken-up by hepatocytes and excreted via the bile (up to 5% of dose). The elimination half-life of gadobenate dimeglumine is approximately 1 hour. It is not metabolized.",
    "mechanism_of_action": "Based on the behavior of protons when placed in a strong magnetic field, which is interpreted and transformed into images by magnetic resonance (MR) instruments. Paramagnetic agents have unpaired electrons that generate a magnetic field about 700 times larger than the proton's field, thus disturbing the proton's local magnetic field. When the local magnetic field around a proton is disturbed, its relaxation process is altered. MR images are based on proton density and proton relaxation dynamics. MR instruments can record 2 different relaxation processes, the T1 (spin-lattice or longitudinal relaxation time) and the T2 (spin-spin or transverse relaxation time). In magnetic resonance imaging (MRI), visualization of normal and pathological brain tissue depends in part on variations in the radiofrequency signal intensity that occur with changes in proton density, alteration of the T1, and variation in the T2. When placed in a magnetic field, Gadobenate Dimeglumine shortens both the T1 and the T2 relaxation times in tissues where it accumulates. At clinical doses, Gadobenate Dimeglumine primarily affects the T1 relaxation time, thus producing an increase in signal intensity. Gadobenate Dimeglumine does not cross the intact blood-brain barrier; therefore, it does not accumulate in normal brain tissue or in central nervous system (CNS) lesions that have not caused an abnormal blood-brain barrier (e.g., cysts, mature post-operative scars).",
    "absorption": "",
    "toxicity": "Gadolinium-based radiocontrast agents like gadobenate dimeglumine are cytotoxic to renal cells. The toxic effects include apoptosis, cellular energy failure, disruption of calcium homeostasis, and disturbance of tubular cell polarity, and are thought to be linked to oxidative stress.",
    "protein_binding": "Plasma protein binding is low, weak, and transient.",
    "metabolism": "Not metabolized.",
    "half_life": "1 hour",
    "route_of_elimination": "Gadobenate ion is eliminated predominately via the kidneys, with 78% to 96% of an administered dose recovered in the urine.",
    "volume_of_distribution": "",
    "clearance": "* 0.093 +/- 0.010 L/hr/kg [healthy male subjects receiving 3 single-dose IV administration with doses from 0.005-0.4 mmol/kg]",
    "structured_indications": [ ]


There are software development kits available to assist the development of your platform, just email for them and they are emailed. After this use the filter objects to choose the right output for you and with the drug effects API output in JSON your project will be clear to design.

Pharmacology API pricing

Samples and trials are freely available if desired, simply write an email and request it. Clients can use the pharmacology data and find out if this is exactly that which clients are searching for. After examinating it, people can decide if they are ready to work with the premium version.

API pricing

The API developed by Drugbank is accessible with 3D secure payment option and prompt access.
Price upon request

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